A dynein-like protein from brain
نویسندگان
چکیده
منابع مشابه
Identification and molecular evolution of new dynein-like protein sequences in rat brain.
RT-PCR cloning was performed to find unknown members of the dynein superfamily expressed in rat brain. Six kinds of degenerate primers designed for the dynein catalytic domain consensuses were used for extensive PCR amplifications. We have sequenced 550 plasmid clones which turned out to include 13 kinds of new dynein-like sequences (DLP1-8, 9A/B, 10-12) and cytoplasmic dynein heavy chain. In t...
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Cytoplasmic dynein, a minus-end-directed microtubule motor, has been implicated in many fundamental cellular processes; however, little is known regarding the underlying molecular machinery that regulates its stability. In Aspergillus nidulans, nuclear distribution gene C (nudC) has been implicated in the regulation of dynein-mediated nuclear migration. Here, we characterize a previously undesc...
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متن کاملDynein ATPase from
sperm with an average velocity of 3.7 "m s-' . This velocity was similar to that of microtubules isolated from bovine brain under the same conditions (average velocity, about 4.1 "m s-'). These results suggest that plant microtubules have an intrinsic ability to interact with and to be translocated by dynein, It is postulated that microtubule-based rnotor proteins, including dynein ATPase, are ...
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ژورنال
عنوان ژورنال: FEBS Letters
سال: 1974
ISSN: 0014-5793
DOI: 10.1016/0014-5793(74)80243-7